This inventor holds 1 USPTO granted patent and 1 published patent application. Top assignees: Florida Memorial University, University of Kansas. Active years: 2014.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:

Years Active: 2014
Title: Rose Mary Stiffin: Innovator in Enzyme Inhibition
Introduction
Rose Mary Stiffin is a notable inventor based in Miami Gardens, Florida, recognized for her contributions to the field of biochemistry and enzyme inhibition. She holds a patent that addresses the inhibition of the enzyme phosphoenolpyruvate carboxykinase (PEPCK), showcasing her innovative approach to biochemical research.
Latest Patents
Stiffin's patent is titled "Inhibitor scaffold for the inhibition of the enzyme phosphoenolpyruvate carboxykinase." This innovative invention revolves around identifying a molecule capable of fitting into and interacting with the PEPCK binding site. Key features of her invention include specific molecular characteristics such as a first terminal substituent with co-planar atoms acting as metal ligands to the active site metal ion PEPCK, criteria for substituents at positions 2 and 3 relative to the first terminal substituent, and a second terminal substituent that acts as a hydrogen bonding acceptor or carries a negative charge. This innovative scaffold could have significant implications for therapeutic interventions involving metabolic disorders.
Career Highlights
Rose Mary Stiffin has made significant strides in her career, with affiliations to prominent academic institutions such as the University of Kansas and Florida Memorial University. Her research and patent work have been instrumental in advancing the understanding of enzyme interactions and their potential inhibitors.
Collaborations
Throughout her career, Stiffin has collaborated with distinguished professionals in the field, including Gerald Carlson and Todd Holyoak. These collaborations have enabled the exchange of innovative ideas and the refinement of research within enzyme inhibition.
Conclusion
Rose Mary Stiffin's contributions to enzyme inhibition illustrate her dedication to scientific innovation. With her patented work and academic affiliations, she stands as a skilled inventor, paving the way for future developments in biochemistry. Her efforts continue to inspire and inform researchers in the area of enzyme research and therapeutic strategies.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile