Rose Mappilakunnel Mathew

Title: Innovations of Rose Mappilakunnel Mathew

Introduction

Rose Mappilakunnel Mathew is a notable inventor based in Collegeville, PA (US). She has made significant contributions to the field of pharmaceutical chemistry, particularly through her innovative work on substituted azabicyclic compounds. With a total of 4 patents, her inventions have the potential to impact therapeutic applications significantly.

Latest Patents

One of her latest patents focuses on substituted azabicyclic compounds. This invention is directed to physiologically active compounds of a specific formula, wherein the compounds exhibit a bicyclic ring system consisting of about 10 to about 13 ring members. The ring is characterized as an azaheterocycle, and the invention also includes N-oxides and pharmaceutically acceptable salts of these compounds. These compounds are known to inhibit the production or physiological effects of TNF and inhibit cyclic AMP phosphodiesterase. Furthermore, the invention encompasses pharmaceutical compositions comprising these compounds, their pharmaceutical use, and methods for their preparation.

Career Highlights

Throughout her career, Rose has worked with prominent companies in the pharmaceutical industry, including Aventis Pharma Limited and Rhone Poulenc Rorer. Her experience in these organizations has contributed to her expertise and innovative capabilities in drug development.

Collaborations

Rose has collaborated with notable colleagues such as Paul Joseph Cox and David John Aldous. These partnerships have likely enriched her research and development efforts, leading to her successful patent applications.

Conclusion

Rose Mappilakunnel Mathew is a distinguished inventor whose work on substituted azabicyclic compounds showcases her innovative spirit and dedication to advancing pharmaceutical science. Her contributions are poised to make a significant impact in the field.