Rosa Liset Ramírez Bartutis

Title: Rosa Liset Ramírez Bartutis: Innovator in Vaccine Development

Introduction

Rosa Liset Ramírez Bartutis is a prominent inventor based in La Habana, Cuba. She has made significant contributions to the field of biotechnology, particularly in the development of vaccines. Her work focuses on innovative solutions to combat viral diseases, showcasing her dedication to public health.

Latest Patents

Rosa holds a patent for a dengue virus vaccine composition. This vaccine comprises at least one antigen based on the dengue virus (DV) capsid protein and the oligonucleotide identified as SEQ ID NO 1. The composition includes a fusion protein formed by the DV2 capsid and domain III of the envelope protein of the same serotype. This formulation has been shown to elicit higher levels of cellular immune response and protection in mice compared to previous formulations. The efficacy of these compositions has also been demonstrated in non-human primates. The vaccine compositions can be monovalent, bivalent, or tetravalent, and are designed to induce a functional immune response to the four viral serotypes.

Career Highlights

Rosa has worked at notable institutions such as the Centro de Ingeniería Genética y Biotecnología. Her research and innovations have positioned her as a key figure in the field of vaccine development. She has dedicated her career to advancing scientific knowledge and improving health outcomes through her inventions.

Collaborations

Rosa has collaborated with Lázaro Gil González, contributing to her research and development efforts. Their partnership has enhanced the impact of her work in the biotechnology sector.

Conclusion

Rosa Liset Ramírez Bartutis is a trailblazer in vaccine innovation, with her work on dengue virus vaccine compositions demonstrating her commitment to advancing public health. Her contributions continue to inspire future generations of scientists and inventors.