This inventor holds 4 USPTO granted patents and 1 published patent application and 1 EPO patent. Top assignees: Macrogenics, Inc., The United States of America as Represented by the Department of Health, The United States of America as Represented by the United States. Active years: 1991-2015.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Location History:
- Derwood, MD (US) (1993)
- Rockville, MD (US) (1991 - 2015)
Company Filing History:
2 out of 133 
1 out of 1,217 
1 out of 3,975 
Years Active: 1991-2015
Title: Ronald L Wilder: Innovator in Autoimmune Disorder Treatments
Introduction
Ronald L Wilder is a prominent inventor based in Rockville, MD (US). He has made significant contributions to the field of immunology, particularly in the treatment of autoimmune disorders. With a total of 4 patents, his work focuses on innovative methods that utilize monoclonal antibodies to address complex health issues.
Latest Patents
Wilder's latest patents include groundbreaking methods for the treatment of autoimmune disorders using immunosuppressive monoclonal antibodies with reduced toxicity. These inventions provide methods for treating, preventing, or ameliorating the symptoms of T cell-mediated immunological diseases, especially autoimmune diseases such as type 1 diabetes and multiple sclerosis. The patents detail the use of anti-human CD3 antibodies that specifically bind to the epsilon subunit within the human CD3 complex. This innovative approach modulates the T cell receptor/alloantigen interaction, thereby regulating T cell-mediated cytotoxicity associated with autoimmune disorders. Additionally, the methods involve the use of modified anti-human CD3 antibodies that exhibit reduced or eliminated effector function and T cell activation compared to non-modified versions.
Career Highlights
Throughout his career, Ronald L Wilder has worked with notable organizations, including Macrogenics, Inc. and the United States of America as represented by the United States. His expertise in immunology and antibody therapies has positioned him as a key figure in the development of treatments for autoimmune diseases.
Collaborations
Wilder has collaborated with esteemed colleagues such as Scott Koenig and Philip W Gold. These partnerships have furthered his research and contributed to the advancement of innovative therapies in the field.
Conclusion
Ronald L Wilder's contributions to the treatment of autoimmune disorders through innovative antibody therapies highlight his role as a leading inventor in the field. His work continues to pave the way for new treatment options that can significantly improve the quality of life for individuals suffering from these challenging conditions.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile