Company Filing History:
Years Active: 2010
Title: Innovations of Ronald L Niece in Cytokine Receptor Research
Introduction
Ronald L Niece is a notable inventor based in Irvine, California. He has made significant contributions to the field of biological agents and their applications in treating inflammatory conditions. His work focuses on the mechanisms of cytokine receptor release, which has implications for various therapeutic approaches.
Latest Patents
Ronald L Niece holds a patent for a biological agent that causes IL-6 receptor release. This patent describes inventions related to the use of biological agents that facilitate the release of cytokine receptors from the surface of cells. One key aspect of this invention is the unexpected finding that extending the length of an exemplary agent at the N-terminus enhances expression and production of the product by at least 10-fold. The extended protein can be utilized to prepare pharmaceutical compositions aimed at treating inflammatory conditions such as rheumatoid arthritis. Additionally, the patent identifies biological agents that cause the release of cytokine receptors not previously recognized as natural enzyme targets, including the IL-1 Type I receptor, IL-1 Type II receptor, and the IL-6 receptor. This disclosure provides valuable products, assays, expression systems, purification methods, and production protocols for developing cytokine receptor releasing proteins as therapeutic agents.
Career Highlights
Ronald L Niece is associated with Meyer Pharmaceuticals LLC, where he continues to advance his research and innovations. His work has garnered attention for its potential impact on the treatment of inflammatory diseases.
Collaborations
Some of his notable coworkers include Tetsuya Gatanaga and Sheldon Broedel, who have collaborated with him on various projects related to his research.
Conclusion
Ronald L Niece's contributions to the field of cytokine receptor research highlight the importance of innovation in developing new therapeutic strategies. His patent on biological agents that facilitate cytokine receptor release represents a significant advancement in the treatment of inflammatory conditions.