Company Filing History:
Years Active: 1996-2001
Title: The Innovative Contributions of Ronald D. Bowditch
Introduction
Ronald D. Bowditch is a prominent inventor based in Encinitas, California. He has made significant contributions to the field of biotechnology, particularly in the development of polypeptides that promote cell attachment. With a total of five patents to his name, Bowditch's work has implications for various applications in medical and research settings.
Latest Patents
One of Bowditch's latest patents focuses on polypeptides for promoting cell attachment. These novel polypeptides, derived from human fibronectin, are designed to bind to integrin receptors expressed by cells. The receptor binding site of human fibronectin begins at a specific amino acid residue and ends at another residue of fibronectin. These polypeptides facilitate the attachment of cells to substrates, either alone or in conjunction with RGD-containing peptides. Additionally, the patent describes vectors, fusion proteins, and antibodies, along with methods for promoting cell attachment and inhibiting cell adhesion.
Another significant patent involves the Platelet GPIII P1.sup.A1 and P1.sup.A2 epitopes. This patent discloses polypeptides and fusion polypeptides that immunologically mimic the native P1.sup.A1 and P1.sup.A2 determinants of platelet protein GPIIIa. It also includes DNA segments and recombinant DNA molecules that encode these polypeptides and fusion polypeptides, as well as methods for expressing and utilizing these determinants. Furthermore, antibodies that immunoreact with one determinant or the other, but not both, are disclosed, along with methods for preparing and using those antibodies.
Career Highlights
Bowditch's career is marked by his innovative research and development in the field of biotechnology. His work has not only advanced scientific understanding but has also paved the way for new therapeutic approaches in medicine. His patents reflect a deep commitment to enhancing cell biology and improving medical outcomes.
Collaborations
Throughout his career, Bowditch has collaborated with notable colleagues, including Mark H. Ginsberg and Edward F. Plow. These collaborations have further enriched his research and contributed to the advancement of their shared field.
Conclusion
In summary, Ronald D. Bowditch is a distinguished inventor whose work in biotechnology has led to significant advancements in cell attachment technologies. His contributions through patents and collaborations continue to impact the scientific community and hold promise for