Roman L Zastawny

Title: Innovations of Roman L Zastawny

Introduction

Roman L Zastawny is a notable inventor based in Etobicoke, Canada. He has made significant contributions to the field of molecular diagnostics, holding a total of four patents. His work focuses on innovative methods for detecting nucleic acids and mutations associated with various diseases.

Latest Patents

One of his latest patents is titled "Capture moieties for nucleic acids and uses thereof." This invention describes a unimolecular probe designed for hybridization to a target nucleic acid sequence. The probe consists of a first nucleic acid sequence that is complementary to the target sequence, known as the target-binding sequence, and a second nucleic acid sequence that can hybridize with the first to form an intramolecular duplex. This probe can be utilized to detect molecules containing the target sequence and can also act as a primer for synthesis or amplification.

Another significant patent is the "Method of detecting mutations associated with thrombosis." This invention provides a method for the simultaneous identification of multiple single base changes in target nucleotide sequences that are markers for cardiovascular diseases, such as deep vein thrombosis. The method employs multiplexed tagged allele-specific primer extension (ASPE) and hybridization of extended primers to a probe, preferably an addressable anti-tagged support.

Career Highlights

Throughout his career, Roman has worked with prominent companies in the molecular diagnostics field, including Luminex Molecular Diagnostics, Inc. and NPS Allelix Corporation. His experience in these organizations has contributed to his expertise and innovative capabilities in developing diagnostic technologies.

Collaborations

Roman has collaborated with several professionals in his field, including Susan Bortolin and Donald G Munroe. These collaborations have likely enhanced his research and development efforts, leading to impactful innovations.

Conclusion

Roman L Zastawny is a distinguished inventor whose work in molecular diagnostics has led to significant advancements in the detection of nucleic acids and associated mutations. His contributions continue to influence the field and improve diagnostic methodologies.