Roman Bradel

Title: Innovations by Roman Bradel in Drug Delivery Systems

Introduction

Roman Bradel is an accomplished inventor based in Kingwood, TX (US). He has made significant contributions to the field of drug delivery systems, particularly through his innovative patent related to adhesives resistant to skin-penetration enhancers. His work is vital in enhancing the effectiveness of drug delivery patches and dressings.

Latest Patents

Bradel holds a patent for "Adhesives resistant to skin-penetration enhancers." This invention involves a graft copolymer designed for use as an adhesive in drug delivery patches or dressings. The copolymer is resistant to dissolution in the presence of skin penetration enhancers, comprising copolymerized acrylic and, optionally, vinyl monomers. The backbone polymer is grafted with polymeric moieties that do not absorb more than 3% by weight of a skin-penetration enhancer under thermodynamic equilibrium at 25°C. The specific grafted polymers are selected from classes such as polybutylene, polysaccharide, poly(ethyleneoxide/propyleneoxide), and polyamide polymers, depending on the enhancers used in a particular drug delivery system.

Career Highlights

Bradel is associated with National Starch and Chemical Investment Holding Corporation, where he applies his expertise in developing innovative solutions for drug delivery. His work has led to advancements in the effectiveness and safety of medical adhesives.

Collaborations

Throughout his career, Bradel has collaborated with notable colleagues, including Deepak Hariharan and Rama S Chandran. These collaborations have contributed to the development of cutting-edge technologies in the field of drug delivery.

Conclusion

Roman Bradel's innovative work in adhesives for drug delivery systems showcases his commitment to improving medical technologies. His patent reflects a significant advancement in the field, promising enhanced efficacy in drug delivery applications.