Company Filing History:
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Years Active: 2017-2020
Title: Innovations in Hemophilia Treatment by Roland W Herzog
Introduction
Roland W Herzog is a prominent inventor based in Gainesville, FL (US), known for his significant contributions to the field of hemophilia treatment. He holds 3 patents that focus on innovative methods to improve protein replacement therapy for patients suffering from hemophilia and other inherited protein deficiencies. His work addresses critical challenges in the treatment process, particularly the formation of inhibitory antibodies.
Latest Patents
One of Herzog's latest patents involves compositions and methods for the suppression of inhibitor formation against coagulation factors in hemophilia patients. This innovative approach utilizes a non-invasive prophylactic protocol that does not require immune suppression or genetic manipulation of the patient's cells. By employing oral delivery of a coagulation factor expressed in chloroplasts and bioencapsulated in plant cells, Herzog's method effectively blocks the formation of inhibitory antibodies. The results have shown that inhibitor titers were mostly undetectable and up to 100-fold lower in treated subjects compared to controls. Furthermore, this treatment has successfully eliminated fatal anaphylactic reactions that can occur after multiple exposures to intravenous coagulation factor protein. The method also has the potential to reverse or reduce undesirable pre-existing inhibitor titers.
Career Highlights
Herzog has had a distinguished career, working with esteemed institutions such as the University of Pennsylvania and the University of Florida Research Foundation, Incorporated. His research has significantly advanced the understanding and treatment of hemophilia, making a lasting impact on patient care.
Collaborations
One of his notable collaborators is Henry Daniell, with whom he has worked on various projects related to hemophilia treatment and innovative therapeutic approaches.
Conclusion
Roland W Herzog's contributions to hemophilia treatment through his innovative patents and research collaborations have paved the way for improved patient outcomes. His work continues to inspire advancements in the field of medical science.