Company Filing History:
Years Active: 2015-2024
Title: Roland Prielhofer: Innovator in Protein Production
Introduction
Roland Prielhofer is a distinguished inventor based in Vienna, Austria. He has made significant contributions to the field of protein production, holding a total of 8 patents. His innovative approaches have advanced the methodologies used in recombinant eukaryotic cell lines.
Latest Patents
Prielhofer's latest patents include groundbreaking methods for producing proteins of interest (POI). One notable patent describes a method that involves culturing a recombinant eukaryotic cell line with an expression construct that includes a regulatable promoter. The process consists of several steps: first, cultivating the cell line with a basal carbon source that represses the promoter; second, using a limited amount of a supplemental carbon source to de-repress the promoter, thereby inducing production of the POI at a transcription rate of at least 15% compared to the native pGAP promoter; and finally, producing and recovering the POI. Additionally, he has developed methods for producing promoter variants, further enhancing the efficiency of protein production.
Career Highlights
Prielhofer is currently employed at Lonza Inc., where he continues to innovate in the field of biotechnology. His work has been instrumental in developing new techniques that improve the yield and efficiency of protein production processes.
Collaborations
Some of his notable coworkers include Diethard Mattanovich and Brigitte Gasser, who have collaborated with him on various projects aimed at advancing protein production technologies.
Conclusion
Roland Prielhofer's contributions to the field of protein production through his patents and work at Lonza Inc. highlight his role as a key innovator in biotechnology. His methods are paving the way for more efficient production processes in the industry.