Rohit Chandrakant Mane

Title: Rohit Chandrakant Mane and Pulse Field Immunotherapy

Introduction

Rohit Chandrakant Mane is an inventor based in Campbell, California. His work includes an invention for tissue treatment and identification using lower-energy irreversible electroporation, a technique described in the patent as Pulse Field Immunotherapy (PFI).

Latest Patents

Mane is associated with 1 patent: “Method, device, and system for pre-biased tissue with lower-energy irreversible electroporation and tissue identification for pulse field immunotherapy.”

The invention describes applying a short-duration electric field to ablate tissue while seeking to preserve intracellular contents. Its waveform first biases tissue toward an electroporation state and then applies a “hammer pulse,” which may use the same or a different polarity. The approach is designed to minimize thermal effects. The patent description also explains that antigens remain in place, where peripheral antigen-presenting cells may take them up and engage the immune system.

The system further describes measuring tissue composition as an applicator moves through normal and diseased tissue. It compares those measurements with a library of characterized Tissue Identity Profiles (TIPs), with the aim of supporting tissue assessment and treatment during a patient’s traditional diagnostic process.

Career Highlights

Mane’s listed invention brings together tissue identification and an electroporation-based treatment approach. The patent describes a system intended to tailor therapy to identified tissue while providing feedback about tissue composition.

Collaborations

Mane is associated with Oso Medical, Inc. His listed coworkers include Denise DeMarais and Nastaran Alinezhadbalalami.

Conclusion

Rohit Chandrakant Mane’s patent focuses on combining tissue profiling with a lower-energy electroporation approach, with the stated goal of supporting targeted treatment and immune engagement.