Company Filing History:
Years Active: 1995-1998
Title: The Innovations of Roger Hart
Introduction
Roger Hart is a notable inventor based in Burlingame, CA (US). He has made significant contributions to the field of biotechnology, particularly in the area of polypeptide refolding. With a total of 6 patents to his name, Hart's work has had a considerable impact on the development of therapeutic proteins.
Latest Patents
One of Roger Hart's latest patents focuses on the refolding of polypeptides, specifically recombinant insulin-like growth factor. This patent describes a composition that includes about 0.1 to 15 mg/mL of a polypeptide in a buffer with a pH of approximately 7-12. The buffer comprises about 5-40% (v/v) of an alcoholic or polar aprotic solvent, along with various salts and chaotropic agents. This innovative method is designed to refold improperly folded polypeptides, which is crucial for the production of functional therapeutic proteins.
Career Highlights
Roger Hart has built a successful career at Genentech, Inc., a leading biotechnology company. His work has contributed to advancements in the production and refinement of biopharmaceuticals. Hart's expertise in polypeptide chemistry has positioned him as a key figure in the field.
Collaborations
Throughout his career, Roger Hart has collaborated with esteemed colleagues, including Stuart E Builder and Philip M Lester. These partnerships have fostered innovation and have led to the development of groundbreaking technologies in biotechnology.
Conclusion
Roger Hart's contributions to the field of biotechnology, particularly in polypeptide refolding, highlight his role as an influential inventor. His work continues to pave the way for advancements in therapeutic protein production.