Company Filing History:
2 out of 18 
2 out of 6 Years Active: 2010-2013
Title: Roberta Castriconi: Innovator in Therapeutic and Diagnostic Methods
Introduction
Roberta Castriconi is a prominent inventor based in Genoa, Italy. She has made significant contributions to the field of therapeutic and diagnostic methods, particularly in cancer research. With a total of two patents to her name, her work focuses on innovative approaches to enhance immune responses against tumors.
Latest Patents
Castriconi's latest patents revolve around therapeutic and diagnostic methods and compositions targeting the 4Ig-B7-H3 protein and its counterpart NK cell receptor. This invention identifies the 4Ig-B7-H3 protein as a tumor-associated molecule that protects tumors from being attacked by natural killer (NK) cells. The patents provide compounds that disrupt the interaction between the 4Ig-B7-H3 protein and its receptor, thereby enhancing NK cell cytotoxicity. Additionally, the compounds can bind to 4Ig-B7-H3-expressing cells to inhibit or eliminate them, making them particularly useful in treating tumors, inflammatory conditions, infections, and transplantation. The patents also include methods for diagnosing diseases by detecting the presence of the 4Ig-B7-H3 protein.
Career Highlights
Throughout her career, Roberta Castriconi has worked with notable organizations such as Innate Pharma and the University of Genova. Her research has significantly advanced the understanding of immune evasion in tumors and has opened new avenues for therapeutic interventions.
Collaborations
Castriconi has collaborated with esteemed colleagues, including Alessandro Moretta and Christina Bottino, who have contributed to her research endeavors.
Conclusion
Roberta Castriconi's innovative work in therapeutic and diagnostic methods highlights her commitment to advancing cancer treatment and improving patient outcomes. Her contributions to the field are invaluable and continue to inspire future research.