Robert W Holt

Title: Innovations in Medical Imaging by Robert W. Holt

Introduction

Robert W. Holt is a notable inventor based in Lebanon, NH (US), recognized for his contributions to the field of medical imaging. With a total of 3 patents, Holt has made significant advancements that enhance the accuracy and effectiveness of medical diagnostics.

Latest Patents

Holt's latest patents focus on a method and apparatus for medical imaging using differencing of multiple fluorophores. This innovative method involves generating corrected fluorescence data of concentrations of a targeted fluorophore in tissue. The process includes administering first and second fluorescent contrast agents to the subject, where the first agent is targeted to the tissue of interest, while the second agent remains untargeted. The tissue is illuminated with light of a first stimulus wavelength, and first data is acquired at an appropriate emissions wavelength. Subsequently, the tissue is illuminated at a second stimulus wavelength, and second data is acquired at a different emissions wavelength associated with the second agent. The difference data is generated by subtracting the second data from the first data. This system allows for stimulus and capture at multiple wavelengths, with image storage memory and subtraction code to perform the method. The corrected data can form a fluorescence image or be used to generate fluorescence tomographic images.

Career Highlights

Holt's career is marked by his dedication to advancing medical imaging technologies. His work at Dartmouth College has positioned him as a key figure in the research community, contributing to innovative solutions that improve patient outcomes.

Collaborations

Holt has collaborated with esteemed colleagues such as Kenneth M. Tichauer and Frederic Leblond, further enhancing the impact of his research through teamwork and shared expertise.

Conclusion

Robert W. Holt's contributions to medical imaging through his innovative patents demonstrate his commitment to improving healthcare technology. His work continues to influence the field and pave the way for future advancements.