Robert T Fraley

Title: The Innovative Legacy of Robert T. Fraley

Introduction

Robert T. Fraley, located in Glendale, Missouri, is an esteemed inventor recognized for his significant contributions to agricultural biotechnology. With a remarkable total of 13 patents to his name, Fraley's work has revolutionized the way plant cells are genetically transformed, enhancing agricultural productivity and sustainability.

Latest Patents

Fraley's latest patents include innovations focused on plasmids for transforming plant cells and genetically transformed plants. One notable patent involves several plasmids designed for genetically transforming plant cells. A primary plasmid, such as pMON120, encompasses a T-DNA border, one or more marker genes, a distinct cleavage site, and a Ti plasmid homology region. A gene, intended for expression in plant cells, can be inserted into this plasmid, resulting in a derivative plasmid like pMON128, which expresses neomycin phosphotransferase in plant cells. This derivative plasmid is then transformed into a microorganism containing a Ti plasmid, enabling the formation of co-integrate plasmids through a single crossover event.

Additionally, his invention concerning genetically transformed, non-tumorous plant cells involves the creation of a modified Ti plasmid, containing both left and right T-DNA borders, encompassing one or more desired genes. This modified Ti plasmid successfully integrates into plant cells, facilitating the transfer of the T-DNA region into the plant genome, ultimately leading to the regeneration of morphologically normal plants that can transmit the desired genes to their descendants.

Career Highlights

Fraley has had a distinguished career primarily with industry leaders like Monsanto Company and Monsanto Technology LLC. His tenure at these organizations has allowed him to pioneer advancements in genetic engineering, particularly in the agricultural sector, leading to the development of numerous successful genetically modified crops.

Collaborations

Throughout his career, Fraley has collaborated with notable experts, including Stephen G. Rogers and Robert B. Horsch. These partnerships have fostered groundbreaking research and innovations in plant biotechnology, further establishing Fraley's reputation as a leader in his field.

Conclusion

Robert T. Fraley's contributions to the field of agricultural biotechnology and his innovative patents have cemented his legacy as a pivotal figure in the evolution of genetically modified plants. His work not only enhances crop yields but also plays a crucial role in addressing global food security challenges.