Ellicott City, MD, United States of America

Robert M Kelly


Average Co-Inventor Count = 3.6

ph-index = 4

Forward Citations = 37(Granted Patents)


Company Filing History:


Years Active: 1993-2002

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5 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Robert M. Kelly

Introduction

Robert M. Kelly is a notable inventor based in Ellicott City, MD (US). He has made significant contributions to the field of biochemistry, particularly in the development of enzymes from hyperthermophilic bacteria. With a total of 5 patents, his work has advanced our understanding of enzyme stability and functionality at high temperatures.

Latest Patents

One of his latest patents focuses on saccharification enzymes derived from hyperthermophilic bacteria. This invention highlights the production of several starch hydrolyzing enzymes, both extracellularly and intracellularly, which maintain their activity at or above 100°C. Among these enzymes are a highly purified α-glucosidase and various amylolytic enzymes, including amylase and pullulanase. Additionally, he discovered a thermostable β-glucosidase that is effective in the degradation of cellulose to D-glucose, remaining active at temperatures up to 95°C.

Another significant patent involves proteolytic enzymes from hyperthermophilic bacteria. Cell-free extracts from Pyrococcus furiosus exhibited exceptionally high levels of proteolytic activity, with only a 30% loss in activity after 24 hours at 98°C. The half-life of this proteolytic activity at that temperature was approximately 60 hours. Furthermore, the enzyme retained substantial activity even in the presence of various denaturing agents, demonstrating its robustness and potential applications in industrial processes.

Career Highlights

Throughout his career, Robert M. Kelly has worked with prestigious organizations, including The Johns Hopkins University and Novo Nordisk A/S. His research has not only contributed to academic knowledge but has also had practical implications in biotechnology and enzyme production.

Collaborations

He has collaborated with notable colleagues such as Stephen H. Brown and Anne K. Robinson, further enhancing the impact of his research through teamwork and shared expertise.

Conclusion

Robert M. Kelly's innovative work in enzyme research exemplifies the importance of scientific inquiry in advancing technology. His patents reflect a commitment to understanding and harnessing the capabilities of enzymes, paving the way for future developments in the field.

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