Robert M Graham

Title: The Innovations of Robert M Graham

Introduction

Robert M Graham is a notable inventor based in Pymble, Australia. He has made significant contributions to the field of structural biology and bioinformatics. With a total of 3 patents to his name, Graham's work focuses on the intricate relationship between protein sequences and their three-dimensional structures.

Latest Patents

One of Graham's latest patents is centered around sequence pattern descriptors for transmembrane structural details. This innovation addresses the core aspects of structural biology and bioinformatics. The patent highlights how the occurrence and conservation of non-canonical conformations are local phenomena. Non-canonical conformations are encoded intra-helically by short peptide sequences, typically heptapeptides. Effective descriptors can be formed for these short sequences by employing training sets. Multiple distinct patterns are created to represent these sequences. A composite descriptor is formed by selecting from among the discovered patterns. This composite descriptor boasts a high level of sensitivity and specificity, along with an enhanced signal-to-noise ratio.

Career Highlights

Graham is currently associated with the International Business Machines Corporation, commonly known as IBM. His work at IBM has allowed him to explore and develop innovative solutions in his field.

Collaborations

Throughout his career, Graham has collaborated with esteemed colleagues such as Isidore Rigoutsos and Peter Riek. These collaborations have further enriched his research and contributions to the scientific community.

Conclusion

Robert M Graham's innovative work in structural biology and bioinformatics has led to significant advancements in understanding protein structures. His patents reflect a deep commitment to enhancing the field through effective descriptors and innovative methodologies.