Stroke-on-Trent, United Kingdom

Robert L Crombie


Average Co-Inventor Count = 2.1

ph-index = 4

Forward Citations = 39(Granted Patents)


Location History:

  • Stoke-on-Trent, GB (2005)
  • Barbridge, GB (2005)
  • Basford, GB (2004 - 2008)
  • Cheshire, GB (2010)
  • Stroke-on-Trent, GB (2011)

Company Filing History:


Years Active: 2004-2011

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7 patents (USPTO):Explore Patents

Title: **The Innovations of Robert L Crombie: A Pioneer in Polynucleotide Technology**

Introduction

Robert L Crombie, an accomplished inventor hailing from Stoke-on-Trent, Great Britain, holds an impressive portfolio of seven patents. His contributions, particularly in the field of biotechnology and genetics, underscore his commitment to advancing scientific understanding and clinical applications.

Latest Patents

Crombie's latest innovations include a polynucleotide that features a ubiquitous chromatin opening element (UCOE). This polynucleotide is designed to enhance the expression of operably-linked genes across multiple tissue types by maintaining chromatin in an open state. His patent describes the mechanisms through which the UCOE can facilitate gene expression, illustrating its application in therapeutic contexts and assays.

Another notable patent focuses on vectors that incorporate 5' extended methylation-free CpG islands along with a 3' selectable marker. This design aims to provide high expression levels of the flanked nucleic acid, crucial for biotechnological applications. These innovations represent significant advancements in genetic engineering and therapeutic development.

Career Highlights

Throughout his career, Crombie has made significant contributions while working with prominent companies such as M. L. Laboratories Plc and Millipore Corporation. His expertise in genetics and molecular biology is reflected not only in his patents but also in his role in enhancing the effectiveness of biotechnological products and methodologies.

Collaborations

Crombie has collaborated with notable professionals in his field, including Michael Antoniou and Steven G Williams. These partnerships have fostered an environment of innovation and have led to the successful development of various scientific projects and patent applications.

Conclusion

Robert L Crombie's contributions to biotechnology and genetics through his patents demonstrate the impact of focused innovation in science. His work embodies the spirit of inquiry and dedication necessary to advance our understanding of genetic mechanisms and their potential therapeutic applications. As technology continues to evolve, contributions from inventors like Crombie will undoubtedly shape the future of medical and scientific advancements.

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