Company Filing History:
Years Active: 1985-1995
Title: The Innovations of Robert L. Alexander
Introduction
Robert L. Alexander is a notable inventor based in Evansville, IN (US). He holds a total of 4 patents that showcase his contributions to the pharmaceutical field. His work primarily focuses on improving the stability and solubility of pharmaceutical compositions.
Latest Patents
One of his latest patents is for a lyophilized cyclophosphamide, which is a pharmaceutical solid composition designed for reconstitution with water. This innovation provides a solution for both oral and parenteral administration. The lyophilized cyclophosphamide solid composition demonstrates improved stability, solubility characteristics, and enhanced appearance compared to existing dry powder pre-mix compositions. The formulation consists of approximately 20 parts by weight of cyclophosphamide, about 1.25-2 parts by weight of water, and between 10-85 parts by weight of excipient, primarily mannitol. Another significant patent involves lyophilized ifosfamide compositions, which utilize urea as the primary excipient. This improved formulation is produced through a modified freeze-drying process, resulting in products with increased heat stability and extended shelf life.
Career Highlights
Throughout his career, Robert L. Alexander has worked with prominent companies such as Mead Johnson & Company and Bristol-Myers Squibb Company. His experience in these organizations has contributed to his expertise in pharmaceutical innovations.
Collaborations
Robert has collaborated with notable coworkers, including Joseph A. Scott and Robert J. Bequette. Their combined efforts have led to advancements in the field of pharmaceuticals.
Conclusion
Robert L. Alexander's contributions to pharmaceutical innovations, particularly in the development of lyophilized compositions, highlight his significant impact on the industry. His work continues to influence the formulation of stable and effective pharmaceutical products.