Location History:
- Winnipeg, CA (1998 - 1999)
- Manitoba, CA (1999)
Company Filing History:
2 out of 199 
1 out of 832,718 Years Active: 1998-1999
Title: Innovations and Contributions of Robert J Matusik
Introduction
Robert J Matusik is a notable inventor based in Winnipeg, Canada. He has made significant contributions to the field of molecular biology, particularly in the study of prostate cancer and androgen regulation. With a total of 3 patents, his work has implications for both research and therapeutic applications.
Latest Patents
Matusik's latest patents include groundbreaking research on androgen regulation with DNA sequences of the rat probasin gene. This patent describes a DNA sequence cloned from the probasin gene promoter region that confers androgen regulation in cell culture and prostate-specific expression in transgenic non-human eukaryotic animals. The research highlights how various PB promoter fragments can impart preferential regulation by androgens compared to other steroid hormones on fused transgenes. Furthermore, alterations in the DNA sequences can enhance the sensitivity of bioassays for androgenic and anti-androgenic materials. This work also explores the significance of amino acid alterations in the androgen receptor on its bioactivity and ability to bind to DNA sequences.
In addition, Matusik has developed transgenic mouse models for prostate cancer, which display progressive forms of prostatic cancer that closely resemble human prostate cancer. These models provide a unique system to study the molecular basis of transformation in normal prostatic cells and the factors influencing the progression to metastatic prostate cancer.
Career Highlights
Matusik has had a distinguished career, primarily associated with the University of Manitoba. His research has led to advancements in understanding prostate cancer and the development of animal models that can be used for testing therapies and understanding carcinogenicity.
Collaborations
Throughout his career, Matusik has collaborated with notable colleagues such as Norman M Greenberg and Jeffrey M Rosen. These collaborations have further enriched his research and contributions to the field.
Conclusion
Robert J Matusik's innovative work in the field of molecular biology has made significant strides in understanding prostate cancer and androgen regulation. His patents and research continue to influence the development of therapeutic strategies for prostatic diseases.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.