Robert J Marder

Title: The Contributions of Robert J. Marder in Cell Analysis Innovation

Introduction

Robert J. Marder, an innovative inventor based in River Forest, IL, has made significant contributions to the field of cell analysis through his groundbreaking patents. With a total of three patents to his name, Marder's work focuses on advanced methodologies for immunoploidy analysis that enhance our understanding of cellular parameters such as DNA.

Latest Patents

Marder's latest patents revolve around methods and apparatuses designed for selecting and analyzing subpopulations of cells or cell objects based on critical parameters, particularly DNA. His patented techniques employ image analysis methods, starting with staining cells using an alkaline phosphatase technique. This includes utilizing a monoclonal antibody that is specific to proteins located in the cytoplasm or on the cell membrane, effectively marking the cells. Additionally, a secondary staining of the DNA in the nucleus is carried out through a Feulgen technique, which destroys the cytoplasm for accurate measurement. Both methods culminate in a process where cells can be gated based on visual parameters, allowing precise examination via digital image processing. The end goal is to generate a quantifiable measurement of DNA, specifically in picograms, thus providing essential insights into cellular characteristics.

Career Highlights

Robert J. Marder works with Cell Analysis Systems, Inc., a company dedicated to advancing technologies in cell analysis. His inventions have fostered greater accuracy in evaluating cellular parameters, which is crucial for biomedical research and clinical applications. His extensive knowledge and innovative thinking in the realm of immunology and cell analysis have positioned him as a valuable asset in his field.

Collaborations

In his career, Marder collaborates with notable individuals in the industry, including his coworker James W. Bacus. Together, they work to enhance the efficacy of cell analysis technologies, driving forward the advancement of research capabilities.

Conclusion

Robert J. Marder's work exemplifies the spirit of innovation in the realm of cellular analysis. With three patents that focus on improving methods for analyzing cell characteristics, he continues to make strides in research applications that can influence medical diagnostics and therapies. His contributions are an invaluable part of the ongoing quest for knowledge in the life sciences.