Location History:
- North Hollywood, CA (US) (1977)
- Ogdensberg, NY (US) (2003)
- Seattle, WA (US) (2015 - 2021)
Company Filing History:
Years Active: 1977-2021
Title: The Innovations of Robert J Livingston
Introduction
Robert J Livingston is a notable inventor based in Seattle, WA, with a significant contribution to the field of biotechnology. He holds a total of 9 patents, showcasing his expertise and innovative spirit in developing advanced methodologies for DNA amplification.
Latest Patents
One of his latest patents focuses on "Compositions and methods for measuring and calibrating amplification bias in multiplexed PCR reactions." This invention describes techniques for standardizing DNA amplification efficiencies using a diverse set of oligonucleotide primers. These primers are essential for amplifying heterogeneous DNA templates, particularly those containing rearranged lymphoid cell DNA that encodes T cell receptors (TCR) or immunoglobulins (IG). The disclosed methods aim to overcome biases that can lead to imprecision in multiplexed high-throughput sequencing, which is crucial for quantifying unique TCR or Ig encoding genomes in samples. The patent also provides a template composition comprising a diverse plurality of template oligonucleotides in substantially equimolar amounts, serving as a calibration standard for amplification primer sets. Additionally, methods for identifying and correcting biased primer efficiency during amplification are included.
Career Highlights
Throughout his career, Robert J Livingston has made significant strides in the biotechnology sector. He has worked with Adaptive Biotechnologies Corporation, where he contributed to groundbreaking research and development in the field. His work has been instrumental in advancing the understanding of DNA amplification techniques.
Collaborations
Robert has collaborated with notable professionals in his field, including Harlan Saul Robins and Christopher Scott Carlson. These collaborations have further enriched his research and innovations.
Conclusion
Robert J Livingston's contributions to biotechnology through his patents and collaborations highlight his role as a leading inventor in the field. His work continues to influence advancements in DNA amplification methodologies, showcasing the importance of innovation in scientific research.