Robert H R Feling

Title: The Innovative Contributions of Robert H R Feling

Introduction

Robert H R Feling is a notable inventor based in Wiesbaden, Germany. He has made significant contributions to the field of biotechnology, particularly in the development of novel compounds for medical applications. With a total of 11 patents to his name, Feling's work has garnered attention for its potential impact on cancer treatment.

Latest Patents

One of Feling's latest patents focuses on salinosporamides and methods of use thereof. This invention is based on the discovery that certain fermentation products from marine actinomycete strains CNB392 and CNB476 serve as effective inhibitors of hyperproliferative mammalian cells. These strains belong to the family Micromonosporaceae, and the generic epithet Salinospora has been proposed for this obligate marine group. The reaction products produced by these strains, classified as salinosporamides, are particularly advantageous in treating neoplastic disorders due to their low molecular weight, low IC values, high pharmaceutical potency, and selectivity for cancer cells over fungi.

Career Highlights

Feling is affiliated with the University of California, where he continues to advance his research in the field of marine biotechnology. His innovative work has positioned him as a key figure in the development of therapeutic agents derived from marine organisms.

Collaborations

Throughout his career, Feling has collaborated with esteemed colleagues such as William H Fenical and Paul R Jensen. These partnerships have further enriched his research and contributed to the advancement of knowledge in his field.

Conclusion

Robert H R Feling's contributions to biotechnology, particularly through his patents on salinosporamides, highlight his role as an influential inventor. His work not only showcases the potential of marine-derived compounds in medicine but also emphasizes the importance of innovation in addressing complex health challenges.