This inventor holds 1 USPTO granted patent and 6 published patent applications. Top assignee: University of California. Active years: 2003.
Company Filing History:
Years Active: 2003
Title: The Innovative Contributions of Robert Grothe
Introduction
Robert Grothe is a notable inventor based in Santa Monica, California. He has made significant contributions to the field of computational biology, particularly in the area of protein function assignment through genome analysis. His work has implications for understanding protein interactions and evolutionary biology.
Latest Patents
Robert Grothe holds a patent for a method titled "Assigning protein functions by comparative genome analysis protein phylogenetic profiles." This innovative computational method provides a system and computer program for inferring functional links from genome sequences. One of the key methods involves identifying pairs of proteins that have homologs in another organism fused into a single protein chain. This trans-genome comparison reveals sequences that act as "Rosetta Stone" sequences, deciphering interactions between proteins. Additionally, the method compares genomic sequences across multiple organisms to create phylogenetic profiles, indicating the presence or absence of proteins across genomes. This profile offers valuable insights into functional links between different protein families.
Career Highlights
Robert Grothe is affiliated with the University of California, where he continues to advance research in computational biology. His work has garnered attention for its innovative approach to understanding protein functions and interactions.
Collaborations
Throughout his career, Robert has collaborated with esteemed colleagues such as Matteo Pellegrini and David S. Eisenberg. These collaborations have further enriched his research and contributed to the advancement of knowledge in the field.
Conclusion
Robert Grothe's contributions to the field of computational biology through his innovative patent demonstrate the importance of interdisciplinary research in understanding complex biological systems. His work continues to influence the study of protein functions and interactions, paving the way for future discoveries.