Company Filing History:
Years Active: 2003-2006
Title: Innovations in Cancer Treatment by Robert Garver, Jr.
Introduction
Robert Garver, Jr. is a notable inventor based in Hoover, AL (US), recognized for his contributions to cancer treatment technologies. With a total of 3 patents, Garver has made significant strides in developing methods and compositions aimed at improving patient outcomes in oncology.
Latest Patents
Garver's latest patents include groundbreaking work on methods and compositions for treating solid tumors. One of his notable inventions is a biodegradable polymer composition that enhances the effectiveness of molecular chemotherapy in conjunction with radiotherapy. This innovative approach utilizes gene therapy combined with radiation therapy to increase cytotoxicity in malignant cells. The invention demonstrates that using the cytosine deaminase gene and 5-fluorocytosine can serve as an effective radiosensitizing strategy. This method may lead to improved tumor control while minimizing normal tissue toxicity compared to conventional systemic administration of 5-fluorouracil. Additionally, Garver has developed a noninvasive method for continuous in vivo monitoring of 5-fluorouracil production through magnetic resonance spectroscopy. He has also constructed an adenovirus encoding the cytosine deaminase gene, which selectively replicates in tumor cells with a defective p53 pathway, along with an adenovirus that encodes a fusion protein of cytosine deaminase and uracil phosphoribosyltransferase.
Career Highlights
Throughout his career, Garver has worked with several prominent organizations, including Guilford Pharmaceuticals, Inc. and the UAB Research Foundation. His work in these institutions has allowed him to further his research and development in cancer therapies.
Collaborations
Garver has collaborated with esteemed colleagues such as Wenbin Dang and Donald J. Buchsbaum, contributing to the advancement of cancer treatment methodologies.
Conclusion
Robert Garver, Jr. stands out as an innovative inventor in the field of cancer treatment, with a focus on enhancing therapeutic strategies through his patented inventions. His work continues to pave the way for improved patient care and outcomes in oncology.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.