Company Filing History:
2 out of 170 
1 out of 9 
1 out of 21,594 
Years Active: 1993-2004
Title: The Innovations of Robert F. Winterkorn
Introduction
Robert F. Winterkorn is a notable inventor based in Rochester, NY (US). He holds a total of 4 patents that showcase his contributions to the field of analytical chemistry. His work primarily focuses on developing dry analytical elements for various assays, which have significant applications in medical diagnostics.
Latest Patents
One of his latest patents is for a dry analytical element for acetaminophen assay. This invention involves a spectrophotometric assay that detects acetaminophen in aqueous fluids using a dry analytical element. The element consists of a support with one or more reagent layers containing aryl acylamidase, which cleaves the amide bond of acetaminophen to produce p-aminophenol. A mild oxidizing agent then oxidizes the p-aminophenol, allowing it to couple with a water-soluble coupling agent to form a dye that can be read at 670 nm. This assay is noted for its precision and accuracy on serum and plasma samples, while also being relatively free from significant interferences. Additionally, it allows measurement over a broad dynamic range.
Another significant patent by Winterkorn is for dry analytical elements used in the determination of protein. This invention enables sensitive and rapid detection and quantitation of protein. The assays utilize a dye that reacts with protein and molybdate ion, resulting in a measurable change in the spectral absorption of the dye. The patent also discloses polymers that stabilize and enhance the accuracy of the assay, along with compounds that reduce interference from bicarbonate.
Career Highlights
Throughout his career, Robert F. Winterkorn has worked with several prominent companies, including Ortho-Clinical Diagnostics, Inc. and Clinical Diagnostic Systems, Inc. His work in these organizations has contributed to advancements in diagnostic technologies.
Collaborations
Winterkorn has collaborated with notable individuals in his field, including James R. Schaeffer and John C. Mauck. These collaborations have likely enriched his research and development efforts, leading to innovative solutions in analytical chemistry.
Conclusion
Robert F. Winterkorn's contributions to the field of analytical chemistry through his patents and career achievements highlight his role as an influential inventor. His work continues to impact medical diagnostics and improve the accuracy of various assays.
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