Company Filing History:
Years Active: 1996-2000
Title: Innovations and Contributions of Inventor Robert E Meyer
Introduction
Robert E Meyer is a notable inventor based in Cary, NC (US), recognized for his significant contributions to the field of therapeutic treatments. With a total of four patents to his name, Meyer has focused on improving the effectiveness of treatments for various medical conditions.
Latest Patents
Meyer’s latest patents include innovative methods aimed at enhancing therapeutic effectiveness. One of his inventions involves the use of an inhibitor of nitric oxide (NO) activity, such as a nitric oxide scavenger or an NO synthase inhibitor, as an adjunct to treat inappropriate tissue vascularization disorders. Another patent focuses on utilizing these inhibitors as antitumor therapies to reduce tumor blood flow and oxygenation. This invention also explores the administration of a nitric oxide scavenger or synthase inhibitor to improve the effectiveness of tumor therapies that employ hypoxic or acidic chemotherapeutic agents or hyperthermia. In specific examples, the administration of cell-free hemoglobin, a nitric oxide scavenger, alongside mitomycin C, a hypoxic cytotoxin, has shown a significant delay in tumor growth in human tumor xenografts in mice compared to mitomycin C alone. Additionally, the administration of an NO synthase inhibitor followed by a substrate of the enzyme results in a specific irreversible reduction of tumor blood flow while restoring normal blood flow.
Career Highlights
Throughout his career, Robert E Meyer has worked with esteemed institutions, including Duke University and Apex Bioscience, Inc. His work has significantly impacted the development of therapeutic strategies in oncology and vascular disorders.
Collaborations
Meyer has collaborated with notable colleagues, including Mark W Dewhirst and Joseph Bonaventura, contributing to advancements in medical research and treatment methodologies.
Conclusion
Robert E Meyer’s innovative patents and collaborations highlight his dedication to improving therapeutic effectiveness in medical treatments. His work continues to influence the field and offers promising avenues for future research and development.
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