Robert E Jordan

Title: Innovations of Robert E. Jordan in Protein Purification

Introduction

Robert E. Jordan is a notable inventor based in Walnut Creek, CA, who has made significant contributions to the field of protein purification and viral inactivation. With a total of three patents to his name, his work focuses on enhancing the safety and efficacy of therapeutic proteins.

Latest Patents

One of Robert E. Jordan's latest patents involves the viral inactivation and purification of active proteins. This innovative process comprises two essential steps. In the first step, an active protein source is treated under conditions sufficient to inactivate any viruses present, utilizing methods such as heat or chemical treatment. The second step involves treating the moderately pure protein source to remove impurities and denatured proteins resulting from the viral inactivation step. A specific example includes the treatment of antithrombin, ensuring viral inactivation while maintaining its biological activity. The resulting concentrate is characterized by high purity, effective virus inactivation, and minimal inactive protein content.

Another significant patent focuses on the purification of blood clotting factors and other blood proteins. This invention discloses a non-carbohydrate sulfated matrix used to isolate and purify these proteins. The procedure involves the adsorption of the proteins onto the matrix, followed by their elution, ensuring a refined and effective purification process.

Career Highlights

Robert E. Jordan has been associated with Miles Laboratories, Inc., where he has applied his expertise in protein purification. His innovative approaches have contributed to advancements in therapeutic protein safety and efficacy.

Collaborations

Throughout his career, Robert has collaborated with notable colleagues, including Jaleh Kilpatrick and Gautam Mitra, enhancing the impact of his research and innovations.

Conclusion

Robert E. Jordan's contributions to the field of protein purification and viral inactivation demonstrate his commitment to advancing therapeutic technologies. His innovative patents reflect a deep understanding of protein chemistry and a dedication to improving healthcare outcomes.