Robert D Barish

Title: Innovations of Robert D Barish

Introduction

Robert D Barish is a prominent inventor based in Pasadena, CA. He has made significant contributions to the field of biotechnology, particularly in RNA interference technologies. With a total of 4 patents, his work has the potential to impact various medical applications.

Latest Patents

One of his latest patents is focused on signal activated RNA interference (saRNAi). This invention provides compositions and methods for saRNAi, preferably in vivo. It includes polynucleotides that switch between inactive and active forms upon interaction with specific chemical signals, such as disease-specific mRNA or miRNA. The interaction is mediated by hybridization, which facilitates the formation of substrates that can be processed by proteins of the RNAi pathway, such as Dicer. Additionally, the invention allows for the formation of an in vivo signaling network through multiple polynucleotides. Another notable patent involves a linker polynucleotide for attaching nanomaterials to a polynucleotidic platform, along with related nanoassemblies and methods.

Career Highlights

Robert D Barish is affiliated with the California Institute of Technology, where he continues to advance his research and innovations. His work is characterized by a strong focus on the intersection of molecular biology and nanotechnology.

Collaborations

Throughout his career, Barish has collaborated with notable colleagues, including William A Goddard, III and Si-ping Han. These collaborations have further enriched his research and contributed to the development of his patented technologies.

Conclusion

Robert D Barish is a distinguished inventor whose work in RNA interference and nanotechnology holds promise for future medical advancements. His contributions continue to shape the landscape of biotechnology and inspire further innovations.