Location History:
- Evanston, IL (US) (1985 - 2010)
- El Cerrito, CA (US) (2011)
Company Filing History:
12 out of 2,126 
1 out of 5,466 
Years Active: 1985-2011
Title: The Innovative Contributions of Robert C. MacDonald
Introduction
Robert C. MacDonald is a prominent inventor based in Evanston, IL (US). He has made significant contributions to the field of biomedical engineering, particularly in the development of novel liposomal technologies. With a total of 12 patents to his name, MacDonald continues to push the boundaries of innovation in his field.
Latest Patents
One of MacDonald's latest patents involves the creation of gas-containing liposomes. This invention provides methods for generating liposomes that contain gas under pressure, specifically focusing on those that can hold a large volume of gas, such as 10 µl of gas per 5 mg of liposomes. Notably, some of these liposomes contain nitric oxide gas, which can be utilized to treat medical conditions that are responsive to nitric oxide, such as intimal hyperplasia. Another significant patent from MacDonald is centered around optimized transfection reagents. This invention comprises mixtures of cationic lipids that enhance DNA delivery vehicles by identifying the optimal hydrophobicity of novel cationic phospholipid derivatives. These derivatives form complexes with DNA, known as lipoplexes, and exhibit improved transfection activity.
Career Highlights
Throughout his career, Robert C. MacDonald has worked with esteemed institutions such as Northwestern University and the University of Texas System. His work has not only advanced scientific understanding but has also paved the way for practical applications in medicine and biotechnology.
Collaborations
MacDonald has collaborated with notable colleagues, including Gary W. Ashley and Miho Shida. These partnerships have contributed to the success of his innovative projects and have fostered a collaborative environment for research and development.
Conclusion
Robert C. MacDonald exemplifies the spirit of innovation through his groundbreaking work in liposomal technologies. His contributions continue to have a lasting impact on the fields of medicine and biotechnology.