Robert B Sim

Title: The Innovations of Robert B Sim

Introduction

Robert B Sim is a notable inventor based in Oxford, GB. He has made significant contributions to the field of biomedical research, particularly in the area of age-related macular degeneration (AMD). His work focuses on identifying agents that can inhibit specific biological interactions, which may lead to advancements in treatment options for AMD.

Latest Patents

Robert B Sim holds a patent titled "Screening assays for binding antagonists of the AMD-associated variant of factor H (H384)." This invention relates to the identification of agents that preferentially inhibit binding to targets such as heparin of the H384 allotypic variant of human complement Factor H. This variant is associated with AMD, and the invention aims to differentiate its binding properties from the non-disease associated form (Y384). The ability to identify antagonists that show differential binding is crucial for developing effective treatments for AMD.

Career Highlights

Sim is affiliated with The University of Manchester, where he conducts his research and contributes to the academic community. His work has implications for understanding the molecular mechanisms underlying AMD and developing therapeutic strategies.

Collaborations

Throughout his career, Robert B Sim has collaborated with esteemed colleagues, including Anthony Day and Simon J Clark. These collaborations have enriched his research and expanded the impact of his inventions.

Conclusion

Robert B Sim's innovative work in the field of biomedical research highlights the importance of understanding genetic variations in diseases like AMD. His patent and ongoing research efforts contribute to the potential development of targeted therapies that could improve patient outcomes.