Company Filing History:

8 out of 712

The Rockefeller University

patents

2 out of 8

Riso National Laboratory

patents

1 out of 444

Research, Incorporated

patents

Years Active: 1981-1998

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11 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 5714467 - Antibacterial and antimalarial hybrid peptides (1998-02-03),

2. 5665705 - Glucagon analogs with serine replacements (1997-09-09),

3. 5585353 - Antibiotic peptides containing D-amino acids (1996-12-17),

4. 5480867 - Glucagon analogs with serine replacements (1996-01-02),

5. 5373053 - Peptide synthesis method and solid support for use in the method (1994-12-13),

6. 5258454 - Peptide synthesis method and solid support for use in the method (1993-11-02),

7. 5143902 - Glucagon analogs with ASP.sup.9 replacements or deletions (1992-09-01),

8. 4879273 - Glucagon homologs and therapeutic use thereof (1989-11-07),

9. 4560676 - N.sup..alpha. -desacetylthymosin.alpha..sub.1 and process (1985-12-24),

10. 4507230 - Peptide synthesis reagents and method of use (1985-03-26),

11. 4293455 - N.sup..alpha. -Desacetylthymosin.alpha..sub.1 and process (1981-10-06),

Title: The Innovations of Robert B Merrifield

Introduction

Robert B Merrifield is a notable inventor based in Creskill, NJ (US), recognized for his significant contributions to the field of biochemistry. He holds a total of 11 patents, showcasing his innovative spirit and dedication to advancing medical science. His work primarily focuses on the development of peptides with therapeutic applications.

Latest Patents

Among his latest patents are the "Antibacterial and Antimalarial Hybrid Peptides." This invention relates to hybrid peptides derived from naturally occurring peptides such as cecropins, attacins, magainins, sarcotoxin, sapecin, bactenecins, alamethidicins, defensins, and PGLa, as well as toxins like streptolysins, melittin, barbatolysin, paradaxins, and delta hemolysin. The hybrid peptides are designed to be easily synthesized and exhibit reduced toxicity. Additionally, the invention includes pharmaceutical compositions containing these hybrid peptides and methods for treating patients infected with organisms susceptible to these peptides. Another significant patent is for "Glucagon Analogs with Serine Replacements." These glucagon analogs are characterized by the substitution of amino acid residues at specific positions and serve as useful adjuncts to insulin therapy.

Career Highlights

Robert B Merrifield has had a distinguished career, working at prestigious institutions such as The Rockefeller University and Riso National Laboratory. His research has led to groundbreaking advancements in peptide synthesis and therapeutic applications.

Collaborations

Throughout his career, Merrifield has collaborated with esteemed colleagues, including James P Tam and Cecilia G Unson. These collaborations have further enriched his research and contributed to the scientific community.

Conclusion

Robert B Merrifield's innovative work in the field of biochemistry has led to significant advancements in the development of therapeutic peptides. His contributions continue to impact medical science and improve treatment options for various infections.

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