This inventor holds 1 USPTO granted patent. Top assignee: Cytomed, Inc.. Active years: 1996.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 1996
Title: The Innovations of Robert B. Lobell
Introduction
Robert B. Lobell is an accomplished inventor based in Watertown, MA (US). He has made significant contributions to the field of biotechnology, particularly in the development of modified ligands for cellular growth.
Latest Patents
Lobell holds a patent for a "Covalent dimer of kit ligand." This invention involves a modified form of KL, the ligand for the c-Kit proto-oncogene. The protein is stabilized by an intermolecular covalent linkage, which enhances its functionality. The process includes the expression of a recombinant protein that is dissolved in denaturant and refolded under specific conditions to create a disulfide-linked dimer. The resulting cysteine dimer kit ligand (KL-CD) demonstrates at least ten-fold greater activity in promoting cell proliferation compared to the native, non-covalently linked KL, as evidenced by in vitro assays.
Career Highlights
Lobell's work at Cytomed, Inc. has been pivotal in advancing research in cell proliferation and cancer treatment. His innovative approach to modifying ligands has opened new avenues for therapeutic applications.
Collaborations
Lobell has collaborated with Karl Henry Nocka, contributing to the development of groundbreaking biotechnological solutions.
Conclusion
Robert B. Lobell's contributions to the field of biotechnology, particularly through his patented innovations, highlight his role as a significant inventor in advancing medical science.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile