Robert B Freedman

Title: Innovations of Robert B Freedman in Recombinant Protein Production

Introduction

Robert B Freedman is a notable inventor based in Canterbury, GB. He has made significant contributions to the field of biotechnology, particularly in the production of recombinant proteins. His innovative methods have the potential to enhance therapeutic applications in medicine.

Latest Patents

Freedman holds a patent titled "Method of increasing production of disulfide bonded recombinant proteins by saccharomyces cerevisiae." This patent discloses a process aimed at increasing the yield of disulfide bonded recombinant proteins produced by yeast, specifically focusing on recombinant secreted proteins. The enzyme protein disulfide isomerase (PDI) plays a crucial role in catalyzing the formation of disulfide bonds in secretory and cell-surface proteins. The patent details the construction of recombinant strains of yeast that overproduce either human PDI or yeast PDI in a regulated manner. These engineered strains demonstrate significantly increased secretion of disulfide bonded proteins, which hold potential therapeutic significance.

Career Highlights

Throughout his career, Freedman has focused on advancing the field of recombinant protein production. His innovative approaches have led to breakthroughs that could improve the efficiency and effectiveness of protein production in biotechnological applications.

Collaborations

Freedman has worked alongside notable colleagues, including Michael F Tuite and Loren D Schultz. Their collaborative efforts have contributed to the advancements in the field of biotechnology and protein engineering.

Conclusion

Robert B Freedman's work in the field of recombinant protein production showcases his innovative spirit and dedication to advancing biotechnology. His patented methods have the potential to significantly impact therapeutic protein production, paving the way for future advancements in the industry.