Rita De Santis

Title: Rita De Santis: Innovator in Pharmaceutical Composition

Introduction

Rita De Santis is a prominent inventor based in Pomezia, Italy. She has made significant contributions to the field of pharmaceutical compositions, holding a total of 11 patents. Her work focuses on innovative solutions for lung diseases and therapeutic delivery systems.

Latest Patents

One of her latest patents is a pharmaceutical composition of oxidized avidin suitable for inhalation. This invention describes oxidized avidin that conditions the lung affected by inoperable or diffuse diseases, enabling the targeted delivery of biotinylated therapeutic agents. Another notable patent involves oxidized avidin with high residency time in treated tissues. This invention details chemically modified avidins that exhibit greater permanence in treated tissues compared to wild-type avidin. The oxidation process involves periodate incubation in the presence of the low-affinity ligand HABA, which prevents protein denaturation during oxidation. The resulting avidins maintain the ability to bind biotinylated agents with therapeutic activity, useful for various medical applications, including brachytherapies.

Career Highlights

Throughout her career, Rita has worked with notable companies such as Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. and Menarini Ricerche S.p.A. Her innovative work has positioned her as a key figure in the pharmaceutical industry.

Collaborations

Rita has collaborated with esteemed colleagues, including Paolo Carminati and Anna Maria Anastasi. These partnerships have further enhanced her research and development efforts in the field.

Conclusion

Rita De Santis is a trailblazer in pharmaceutical innovation, with a focus on improving therapeutic delivery systems for lung diseases. Her contributions continue to impact the medical field positively.