Location History:
- Milano, IT (1989)
- Milan, IT (1983 - 1992)
Company Filing History:
Years Active: 1983-1992
Title: Rinaldo Del Bono: Innovator in Pharmaceutical Purity
Introduction
Rinaldo Del Bono is a notable inventor based in Milan, Italy. He has made significant contributions to the field of pharmaceuticals, particularly in the preparation of high-purity dermatan sulphate. With a total of 4 patents to his name, Del Bono's work is recognized for its innovative approaches to utilizing animal organs rich in mucopolysaccharides.
Latest Patents
Del Bono's latest patents focus on processes for preparing dermatan sulphate (DS) of pharmaceutical purity. The first patent outlines a method that includes stabilizing fresh organs by freezing them, micronizing the material with an aqueous CaCl.sub.2 solution, and digesting the homogenate with proteolytic enzymes at alkaline pH and low temperature. The process continues with acidifying, heating, and filtering the lysate, followed by treating the filtrate with quaternary ammonium salts to precipitate the DS or all mucopolysaccharides selectively. Finally, the DS is recovered and purified from the ammonium salt complex.
Career Highlights
Rinaldo Del Bono is currently associated with Mediolanum Farmaceutici, S.r.l., where he continues to innovate in the pharmaceutical sector. His work has been instrumental in advancing the methods of extracting and purifying essential compounds from biological materials.
Collaborations
Del Bono has collaborated with notable colleagues such as Luigi De Ambrosi and Gianni Ferrari. Their combined expertise has contributed to the successful development of his patented processes.
Conclusion
Rinaldo Del Bono stands out as a significant figure in the field of pharmaceutical innovations. His patents reflect a commitment to enhancing the purity and efficacy of important pharmaceutical compounds.