Company Filing History:
3 out of 4 
2 out of 769 
2 out of 3,446 
Years Active: 2015-2018
Title: Innovations and Contributions of Richard W. Fitch
Introduction
Richard W. Fitch is a notable inventor based in Terre Haute, IN (US), recognized for his significant contributions to the field of pharmacology and molecular biology. With a total of 4 patents, his work focuses on developing novel therapeutic agents that target critical biological pathways.
Latest Patents
One of his latest patents involves nicotinic acetylcholine receptor agonists. This invention provides novel compounds, such as phantasmidine and its derivatives, aimed at treating various disorders responsive to these agonists. Conditions like Alzheimer's disease, schizophrenia, Myasthenia Gravis, Tourette's syndrome, Parkinson's disease, epilepsy, pain, and cognitive dysfunction can potentially benefit from these innovative treatments.
Another significant patent by Fitch is related to small molecule inhibitors of replication protein A (RPA) that act synergistically with cisplatin. RPA plays an essential role in DNA replication, recombination, and repair. His research identified small molecule inhibitors that disrupt RPA's binding activity to single-stranded DNA, demonstrating increased apoptotic cell death in lung cancer cell lines. The findings suggest that these inhibitors could enhance the efficacy of existing chemotherapeutic regimens.
Career Highlights
Richard W. Fitch has had a distinguished career, contributing to research and development in various academic and professional settings. He has worked at Indiana State University and Indiana University, where he has made significant strides in his field.
Collaborations
Throughout his career, Fitch has collaborated with esteemed colleagues, including John J. Turchi and Thomas F. Spande. These partnerships have furthered his research and innovation in the pharmaceutical sciences.
Conclusion
Richard W. Fitch's innovative work in developing therapeutic agents showcases his commitment to advancing medical science. His contributions have the potential to impact the treatment of various serious health conditions significantly.