Company Filing History:
Years Active: 1976
Title: Richard Nelson Hurd: Innovator in Chemical Conversions
Introduction
Richard Nelson Hurd is a notable inventor based in Wilmette, IL (US). He has made significant contributions to the field of chemistry, particularly in the conversion of specific compounds that have important biological implications.
Latest Patents
Hurd holds a patent for the conversion of (10'S)-zearalenone to (10'R)-zearalanone. This innovative process involves opening the lactone ring of zearalenone in an alkaline medium to produce a hydroxy acid. The hydroxy acid is then esterified to create a hydroxy ester, which is tosylated. Following this, the tosyl ester is reacted with a tetraalkyl ammonium alkyl ester to invert the (S) structure to the (R) structure. Finally, the lactone is reformed and hydrogenated to yield (10'R)-zearalanone. This compound, when mixed with (10'S)-zearalenone, enhances the uterotropic activity of the latter.
Career Highlights
Richard Nelson Hurd is associated with Commercial Solvents Corporation, where he has applied his expertise in chemical processes. His work has contributed to advancements in the understanding and application of zearalenone derivatives.
Collaborations
Hurd has collaborated with Charles Allan Peters, furthering research and development in their field.
Conclusion
Richard Nelson Hurd's innovative work in chemical conversions has led to significant advancements in the understanding of zearalenone and its derivatives. His contributions continue to impact the field of chemistry and its applications in biological sciences.