This inventor holds 12 USPTO granted patents. Top assignees: Alseres Pharmaceuticals, Inc., Children's Medical Center Corporation, National Taiwan University. Active years: 2002-2024.
Location History:
- North Easton, MA (US) (2002 - 2008)
- Boston, MA (US) (2013 - 2017)
- Cambridge, MA (US) (2021)
- Mendon, MA (US) (2012 - 2024)
Company Filing History:
5 out of 6 
3 out of 1,072 
2 out of 1,391 
Years Active: 2002-2024
Title: Richard M Thorn: Innovator in Gene Therapy and Neurological Treatments
Introduction
Richard M Thorn is a prominent inventor based in North Easton, MA (US). He has made significant contributions to the field of gene therapy, particularly in the treatment of neurological disorders. With a total of 12 patents, Thorn's work has the potential to impact the lives of many patients suffering from rare genetic conditions.
Latest Patents
One of Thorn's latest patents focuses on gene therapy for aromatic-amino acid decarboxylase (AADC) deficiency. This invention outlines compositions and methods for treating AADC deficiency, particularly in pediatric subjects. The method involves providing a pharmaceutical formulation comprising an rAAV2-hAADC vector and delivering it stereotactically to target sites in the brain. The patent also discusses the option of administering a therapeutically effective dose of dopamine-antagonist, such as risperidone, to enhance treatment efficacy. Additionally, Thorn has developed frataxin expression constructs aimed at treating Friedreich's Ataxia, showcasing his commitment to addressing complex neurological disorders.
Career Highlights
Throughout his career, Richard M Thorn has worked with notable organizations, including Alseres Pharmaceuticals, Inc. and Children's Medical Center Corporation. His experience in these companies has allowed him to refine his expertise in gene therapy and contribute to groundbreaking research in the field.
Collaborations
Thorn has collaborated with esteemed colleagues, including Marsha A Moses and Dmitri G Wiederschain. These partnerships have further enriched his research and development efforts, leading to innovative solutions in medical treatments.
Conclusion
Richard M Thorn's contributions to gene therapy and neurological treatments exemplify his dedication to advancing medical science. His innovative patents and collaborations highlight the importance of research in improving patient outcomes.