Richard L Frock

Title: Richard L Frock: Innovator in Genome Research

Introduction

Richard L Frock is a notable inventor based in Jamaica Plain, MA (US). He has made significant contributions to the field of genome research, particularly in the detection of double-strand breaks in DNA. His work is essential for understanding various biological processes and the impact of external agents on genetic material.

Latest Patents

Richard L Frock holds 1 patent related to methods for detecting recurrent and non-specific double-strand breaks in the genome. His patent describes innovative methods and systems for high throughput, genome-wide translocation sequencing (HTGTS) and the detection of double-stranded DNA break (DSB) locations. The methods involve generating DSBs in a nucleic acid sequence and performing nested PCR with specific primers. This enhanced HTGTS approach allows for the measurement of various DNA DSB activities, whether intrinsic to biological systems or caused by external agents.

Career Highlights

Richard L Frock is associated with the Children's Medical Center Corporation, where he applies his expertise in genomic research. His work has implications for understanding genetic disorders and developing potential therapeutic strategies.

Collaborations

He has collaborated with notable colleagues in the field, including Frederick W Alt and Jiazhi Hu. Their combined efforts contribute to advancing research in genome integrity and repair mechanisms.

Conclusion

Richard L Frock's innovative work in genome research highlights the importance of understanding DNA double-strand breaks and their implications for health and disease. His contributions continue to influence the field and pave the way for future discoveries.