Salisbury, United Kingdom

Richard J Manchee


Average Co-Inventor Count = 3.0

ph-index = 1

Forward Citations = 6(Granted Patents)


Company Filing History:


Years Active: 1981

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1 patent (USPTO):Explore Patents

Title: Richard J Manchee: Innovator in Immunogenic Cell Envelope Preparations

Introduction

Richard J Manchee is a notable inventor based in Salisbury, GB. He has made significant contributions to the field of immunology, particularly through his innovative work on cell envelope preparations. His research focuses on developing antigenically-active cell envelope fractions from bacterial cells, which have important implications for vaccine development.

Latest Patents

Richard J Manchee holds a patent for "Immunogenic cell envelope preparations." This patent describes a method for isolating an antigenically-active cell envelope fraction from bacterial cells, specifically Bordetella pertussis. The process involves disrupting the bacterial cells, separating the cell envelopes from other components, and extracting the envelopes using a zwitterionic surfactant solution. The resulting cell envelope preparation is precipitated using a lower alkyl alcohol, preferably ethanol. This innovative approach results in a highly protective cell envelope fraction that has a significantly reduced lipopolysaccharide content, thereby minimizing the risk of undesirable side effects from vaccination.

Career Highlights

Richard J Manchee's career is marked by his dedication to advancing vaccine technology. His work has been instrumental in improving the safety and efficacy of vaccines, particularly those targeting Bordetella pertussis. With a patent count of 1 patent, he has established himself as a key figure in the field of immunogenic research.

Collaborations

Throughout his career, Richard has collaborated with esteemed colleagues, including Derek C Ellwood and Andrew Robinson. These partnerships have further enhanced the impact of his research and contributed to the advancement of immunological studies.

Conclusion

In summary, Richard J Manchee is a pioneering inventor whose work on immunogenic cell envelope preparations has the potential to revolutionize vaccine development. His innovative methods and collaborative efforts continue to make significant strides in the field of immunology.

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