Company Filing History:
Years Active: 1978-1995
Title: The Innovations of Richard E. Heiney
Introduction
Richard E. Heiney is a notable inventor based in Greenwood, IN (US). He has made significant contributions to the field of pharmaceuticals, particularly in the development of processes related to insulin and antibiotics. With a total of 3 patents, Heiney's work has had a meaningful impact on medical science.
Latest Patents
Heiney's latest patents include a process for transforming a human insulin precursor to human insulin. This specification describes a process for converting a human insulin precursor to human insulin, which comprises treating such human insulin precursor with trypsin and carboxypeptidase B in an aqueous medium containing per mole of human insulin precursor from about 0.1 to about 10 moles of one or more metal ions of those metals having Atomic Numbers 21 to 34, 39 to 52, 57 to 84, and 89 to 92. Another significant patent is for a process for 3-hydroxymethyl cephalosporin sulfones. This invention relates to a process for preparing 7-(S)-acylamino-3-hydroxymethyl-3-cephem-4-carboxylic acid sulfones and the salts and esters thereof. The instant process involves contacting a 7-(S)-acylamino-3-acetoxymethyl cephalosporin sulfone in an aqueous solution buffered from about pH 6 to about pH 8 with citrus acetylesterase, which is immobilized on silica gel. The 3-hydroxymethyl cephalosporin sulfones produced by the process of this invention are intermediates in the synthesis of 1-oxa .beta.-lactam antibiotics.
Career Highlights
Heiney has had a distinguished career, working at Eli Lilly and Company, a leading pharmaceutical firm. His innovative approaches to drug development have contributed to advancements in medical treatments and therapies.
Collaborations
Heiney has collaborated with notable colleagues such as Bruce H. Frank and Walker E. Prouty. These partnerships have fostered a collaborative environment that encourages innovation and the sharing of ideas.
Conclusion
Richard E. Heiney's contributions to the field of pharmaceuticals through his patents and collaborations highlight his role as a significant inventor