Company Filing History:
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Years Active: 1986-2003
Title: Richard D Palmiter: Innovator in Transgenic Research
Introduction
Richard D Palmiter is a prominent inventor based in Seattle, WA (US). He has made significant contributions to the field of biotechnology, particularly in the synthesis of functional human hemoglobin and other proteins in transgenic non-human mammals. With a total of 7 patents, his work has paved the way for advancements in genetic engineering and therapeutic applications.
Latest Patents
Among his latest patents, one notable invention is the synthesis of functional human hemoglobin and other proteins in erythroid tissues of transgenic non-human animals. This invention is based on the discovery that two of the five hypersensitivity sites of the β-globin locus are sufficient to result in high-level expression of human α- or β-globin transgenes. Another significant patent involves novel recombinant nucleic acid vectors that can produce α-globin and other proteins in quantity within the red blood cells of transgenic animals or cell cultures of erythroid lineage. These vectors comprise major DNase I hypersensitivity sites associated with the β-globin locus, allowing for the creation of transgenic animals that express human hemoglobin in their erythroid tissues.
Career Highlights
Richard D Palmiter has had a distinguished career, working with esteemed institutions such as the University of Washington and the UAB Research Foundation. His research has significantly impacted the field of genetic engineering, particularly in the development of transgenic models for studying human diseases.
Collaborations
Throughout his career, Palmiter has collaborated with notable scientists, including Ralph L Brinster and Tim M Townes. These collaborations have further enhanced the scope and impact of his research in the field of biotechnology.
Conclusion
Richard D Palmiter's innovative work in transgenic research has led to important advancements in the synthesis of human proteins, showcasing his role as a key inventor in the biotechnology sector. His contributions continue to influence the development of therapeutic solutions and genetic engineering techniques.