Company Filing History:
Years Active: 2023-2024
Title: Richard Beswick: Innovator in Cellular Technology
Introduction
Richard Beswick is a prominent inventor based in London, GB. He has made significant contributions to the field of cellular technology, particularly in the development of methods for preparing genetically modified T cells. With a total of 2 patents, his work is paving the way for advancements in medical treatments.
Latest Patents
One of Richard's latest patents is a method of preparing T cells with increased activity. This invention provides a method for creating a population of genetically modified cells that include a chimeric antigen receptor (CAR) or a transgenic T-cell receptor (TCR). The process involves starting with a population of cells, depleting those that express a target antigen, and introducing a nucleic acid sequence that encodes a CAR or transgenic TCR against the target antigen. This innovation also encompasses genetically modified cells and pharmaceutical compositions aimed at treating or preventing diseases.
Another significant patent involves retroviral and lentiviral vectors. This invention presents a viral vector with a mitogenic T-cell activating transmembrane protein. The protein includes a mitogenic domain that binds a mitogenic tetraspanin and a transmembrane domain. When T-cells or Natural Killer cells are transduced by this viral vector, they are activated by the mitogenic T-cell activating transmembrane protein, enhancing their functionality.
Career Highlights
Richard Beswick is currently associated with Autolus Limited, a company focused on developing innovative T cell therapies. His work at Autolus has been instrumental in advancing the field of immunotherapy, particularly in the treatment of various diseases.
Collaborations
Richard has collaborated with notable colleagues, including Martin Pulé and Ekaterini Kotsopoulou. These partnerships have contributed to the success of his projects and the advancement of cellular technology.
Conclusion
Richard Beswick is a key figure in the field of cellular technology, with innovative patents that have the potential to transform medical treatments. His work continues to inspire advancements in the preparation and application of genetically modified T cells.