Richard A Blumenthal

Title: Richard A. Blumenthal: Innovator in Enzyme Substrates

Introduction

Richard A. Blumenthal is a notable inventor based in Charlestown, MA (US). He has made significant contributions to the field of enzyme substrates, particularly in the stabilization and reduction of background fluorescence. His innovative work has implications for various applications in biochemistry and enzymology.

Latest Patents

Richard A. Blumenthal holds a patent for the "Stabilization and reduction of background fluorescence of hydroxy - Hydroxy coumarin ester enzyme substrates." This patent describes a method where hydroxy coumarin ester enzyme substrates can be stored in a strong base at pH above 11. This approach stabilizes the substrate against premature hydrolysis of the ester bond and reduces the level of contaminating hydroxy coumarin. When diluted in buffer at pH below 11 shortly before use in an enzyme assay, the substrate solution provides low background fluorescence.

Career Highlights

Richard A. Blumenthal is associated with E.I. du Pont de Nemours and Company, a leading company in the field of science and technology. His work at this organization has allowed him to contribute to advancements in enzyme technology and related fields.

Collaborations

Throughout his career, Richard has collaborated with esteemed colleagues such as Hon-Peng P. Lau and Esther K. Yang. These collaborations have further enriched his research and innovation in enzyme substrates.

Conclusion

Richard A. Blumenthal is a distinguished inventor whose work has significantly impacted the field of enzyme substrates. His innovative patent and collaborations highlight his contributions to science and technology.