Company Filing History:
11 out of 592 
4 out of 165 
1 out of 166 
Years Active: 1994-1998
Title: Innovator Rene Imwinkelried: Pioneer in Antiviral Compounds
Introduction
Rene Imwinkelried, situated in Brig-Glis, Switzerland, is an esteemed inventor with an impressive portfolio of 17 patents. His research focuses on developing innovative chemical compounds, particularly those with antiviral applications.
Latest Patents
Among his latest inventions is the N-(2-amino-4, 6-dichlopyrimidine-5-yl)formamide, a novel pyrimidine derivative designed for use in the production of antiviral nucleotide derivatives. This compound is synthesized through a complex process involving the cyclization of an aminomalonic ester with guanidine or its salt in the presence of a base to yield 2,5-diamino-4,6-dihydroxypyrimidine or its salt. This intermediate is further chlorinated with a chlorinating agent alongside an amide to create 4,6-dichloropyrimidine. Finally, reacting this product with an aqueous solution of a carboxylic acid results in the formation of N-(2-amino-4,6-dichloropyrimidine-5-yl)formamide. Additionally, he has contributed to the development of various other compounds, such as 4,6-dichloropyrimidine and several nucleosides that offer antiviral benefits and biologically active oligonucleotides.
Career Highlights
Rene's career has largely been shaped by his tenure at significant organizations, including Lonza Inc. and Lonza AG. These roles provided him with the resources and collaborative environment necessary to innovate and refine his groundbreaking chemical processes and compounds.
Collaborations
Throughout his journey, Rene has worked alongside prominent scientists such as Gerhard C. Stucky and Jacques Gosteli. These collaborations have bolstered his research, contributing to the success of various projects and the expansion of his patent portfolio.
Conclusion
Rene Imwinkelried stands out as a remarkable inventor in the field of chemistry, particularly within antiviral research. His commitment to innovation and collaboration with esteemed colleagues has enabled the development of novel compounds that hold promise for significant medical advancements. As his career progresses, the impact of his inventions will likely resonate across the pharmaceutical industry, highlighting the importance of creativity and research in the fight against viral diseases.