Remkes A Scheele

Title: Remkes A Scheele: Innovator in Non-Canonical Amino Acids

Introduction

Remkes A Scheele is a notable inventor based in Nijeveen, Netherlands. He has made significant contributions to the field of biochemistry, particularly in the synthesis of non-canonical amino acids. With a total of 3 patents, his work has implications for various applications in biotechnology and pharmaceuticals.

Latest Patents

Scheele's latest patents focus on methods and enzyme catalysts for the synthesis of β-substituted tryptophan compounds. The disclosed methods involve combining an unsubstituted or substituted indole, a β-substituted serine, and a tryptophan synthase β-subunit (TrpB). The resulting mixture is maintained under specific conditions to facilitate the formation of β-substituted tryptophan. Notably, the TrpB contains at least one amino acid mutation that promotes the formation of an amino-acrylate intermediate. Additionally, new TrpB variants and β-substituted tryptophan analogs are described in his patents.

Career Highlights

Remkes A Scheele is affiliated with the California Institute of Technology, where he continues to advance research in his field. His innovative approaches have garnered attention and recognition within the scientific community.

Collaborations

Some of his notable coworkers include Christina E Boville and Sabine Brinkmann-Chen, who have collaborated with him on various research projects.

Conclusion

Remkes A Scheele's contributions to the synthesis of non-canonical amino acids highlight his role as an influential inventor in biochemistry. His patents and ongoing research continue to pave the way for advancements in the field.