This inventor holds 1 USPTO granted patent. Top assignee: University of Virginia Patent Foundation. Active years: 1998.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 1998
Title: Reiko Horikawa: Innovator in Molecular Cloning
Introduction
Reiko Horikawa is a distinguished inventor based in Tokyo, Japan. He has made significant contributions to the field of molecular biology, particularly in the area of growth hormone research. His innovative work has led to advancements in understanding the mechanisms of hormone receptor interactions.
Latest Patents
Reiko Horikawa holds a patent for the molecular cloning of the ovine pituitary growth hormone releasing hormone (GHRH) receptor. This patent details a unique binding assay utilizing iodinated GHRH probes to characterize the receptor binding. Additionally, he has constructed photoaffinity GHRH probes that facilitate photolabeling and characterization of the receptor. His work also includes the development of high-affinity biotinylated GHRH analogs. The solubilization of GHRH-R/GHRH complexes and the extraction of specifically bound GHRH using a mild detergent solution, followed by affinity chromatography, leads to a substantially purified GHRH-R isolate. The electrophoretic treatment of this isolate produces GHRH-R of sufficient purity for receptor sequencing. Furthermore, he has accomplished the cloning of a gene encoding polypeptides with GHRH-R activity using a bacterial host, with expression in a mammalian cell line.
Career Highlights
Reiko Horikawa is affiliated with the University of Virginia Patent Foundation, where he continues to advance his research. His work has been pivotal in enhancing the understanding of growth hormone mechanisms and their applications in biotechnology.
Collaborations
Reiko has collaborated with notable colleagues, including Michael Oliver Thorner and Bruce D Gaylinn. Their combined expertise has contributed to the success of various research projects in the field.
Conclusion
Reiko Horikawa's innovative contributions to molecular cloning and hormone research have established him as a key figure in the scientific community. His work continues to influence advancements in biotechnology and molecular biology.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile