Company Filing History:
Years Active: 1997
Title: The Innovations of Regina E Brigelius-Flohe'
Introduction
Regina E Brigelius-Flohe' is a prominent inventor based in Roetgen, Germany. She has made significant contributions to the field of biotechnology, particularly in the development of plasmids for protein expression. Her work has implications for therapeutic applications, showcasing her innovative spirit and dedication to scientific advancement.
Latest Patents
Regina holds a patent for "Plasmids, their construction and their use in the manufacture of a." This patent describes plasmids containing synthetic DNA sequences that are suitable for the expression of the intermediate protein of the recombinant scu-PA. The plasmids are designed to achieve expression rates far higher than those obtainable through prior methods. They include operons with a regulatable promoter, a Shine-Dalgarno sequence, a start codon, and a synthetic structural gene with selected codon usage. The preparation of these plasmids allows for the high-yield expression of therapeutically useful proteins.
Career Highlights
Regina is associated with Gruenenthal GmbH, where she continues to push the boundaries of biotechnology. Her innovative work has led to advancements in the production of recombinant proteins, which are crucial for various medical applications. With her expertise, she has established herself as a key figure in her field.
Collaborations
Throughout her career, Regina has collaborated with notable scientists, including Leopold Flohe' and Wolfgang Hillen. These collaborations have enriched her research and contributed to the success of her projects.
Conclusion
Regina E Brigelius-Flohe' exemplifies the spirit of innovation in biotechnology through her groundbreaking work on plasmids and protein expression. Her contributions continue to impact the field and pave the way for future advancements.