Reddy Venkat Mekala

Title: Reddy Venkat Mekala: Innovator in Functional Assays

Introduction

Reddy Venkat Mekala is a prominent inventor based in Hyderabad, Telangana, India. He has made significant contributions to the field of pharmacology through his innovative work on functional assays. His expertise lies in the development of assays that measure receptor activity, which is crucial for drug discovery and development.

Latest Patents

Reddy holds a patent for a "Functional assay for 5-HT2A, histamine H1 or adrenergic alpha 1B receptors." This invention provides a novel functional assay for 5-HT, histamine H1, or adrenergic alpha 1B receptors by measuring intracellular cyclic adenosine monophosphate (cAMP) levels utilizing a reporter gene-driven cell-based assay. The novel assay offers both binding affinity and mode of action of compounds in a single set. It is useful in identifying compounds acting through these receptors and categorizing them into agonist, partial agonist, inverse agonist, and antagonist classes. Furthermore, the assay can be scaled up to any high-throughput format, enhancing its utility in research.

Career Highlights

Reddy Venkat Mekala is associated with Suven Life Sciences Limited, where he applies his expertise in pharmacology and assay development. His work has contributed to advancing the understanding of receptor interactions and their implications in drug development.

Collaborations

Reddy has collaborated with notable colleagues, including Ishtiyaque Ahmad and Reddy Muddukrishna Chillakur. These collaborations have fostered a productive environment for innovation and research within the company.

Conclusion

Reddy Venkat Mekala is a distinguished inventor whose work in functional assays has the potential to significantly impact drug discovery. His innovative approach to measuring receptor activity is paving the way for advancements in pharmacological research.